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We show that a single point mutation on this triplet abolishes the cell-binding activity of IBDV-derived subviral particles (SVP), and abrogates the recovering of infectious IBDV by reverse genetics without affecting the overall SVP architecture.
We ALL have this gene, but my particular family has a mutation on this tumor suppressor gene.
We examined the effect of SSN8 mutation on this process in the MATα and MATa wild-type strain background.
Since swarming of P. aeruginosa is dependent on rhamnolipid production [8], we evaluated the impact of the mutation on this biosynthesis.
The most frequent mutation on this gene associated to the albino phenotype is a G to C transversion at the position 390 (in bold).
The effects on yvcA promoter activity prompted us to investigate the effects of the degS S76D mutation on this and the other social behavioural traits pellicle formation and swarming that are regulated by low levels of DegU∼P.
Similar(43)
The catalytically impaired hMYH variant R260Q was found in one patient carrying this mutation on one allele.
Once a mutant version of the bait (A) is found, one can study the influence of this mutation on the phenotype.
This suggests a specific effect of this mutation on the initiation in the non-coding region of mtDNA, while elongation elsewhere seemed to be less affected.
Mapping of the location of this mutation on the structure of MtbHadAB reveals that the mutation is located at the N-terminal end of αHD and lies at the bottom of the flavonoid binding pocket (Fig. 6C).
Using computations and experiments, we examine the impact of this mutation on the stability and conformational dynamics of the mini-intein splicing domain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com