Sentence examples for mutant on this from inspiring English sources

To further confirm the crucial role played by AP-1 transcription factors in the PMA-dependent enhancer activity of fragment 5103, we evaluated the effects of overexpression of a dominant negative A-Fos mutant on this activity in transient transfection experiments.

A phospho-mimetic mutant on this site displayed enhanced casein kinase I-mediated phosphorylation when compared with wild-type in vitro (307 ± 12%; mean±S.E.M., n = 5) (Fig.  3A).

Due to its additional activity on fructose [ 54], LXR1 could also be involved in the increased growth of the wild-type and the decreased growth in the env1 mutant on this carbon source in light.

We assessed then the impact of the overexpression of this mutant on the levels of p62 (SQSTM1/sequestosome 1), an endogenous autophagy substrate (27).

Interestingly, no significant effect of Y477F ezrin on the rate of primary growth of AC2M2 tumors was observed, thus mimicking the effect of this mutant on the growth behaviour of AC2M2 cells in 3D culture.

However, the effect of extracellular α-Syn on cellular activation and immune mediators, as well as the impact of familial PD-linked α-Syn mutants on this stimulation, are still largely unknown.

To further characterize the effects of the H4-R36A mutant on the transcription elongation process, we carried out additional ChIP experiments to determine the effects of this histone mutant on Pol II and bulk nucleosome occupancy across the PMA1 and FBA1 genes.

In a season of crime fighter against crime fighter, super power vs. super power films, this mutant-on-mutant spectacular has the most depth, innovation, majesty and visual wonder.

Here, we investigated the effects on plant cells of metabolite complexes secreted by Trichoderma atroviride wild type P1 and a deletion mutant of this strain on the level of cytosolic free Ca2+ and activation of defense responses.

We therefore compared the effects of the microcystin-producing wild type M. aeruginosa PCC7806 and the mcy- mutant of this strain on the relative expression of genes involved in basic metabolism.

However only around 60% of Vβ5.1 and Vβ11 bearing cells were deleted in the Foxn1Δ/Δ mutant mice on this genetic background.