Sentence examples for mutation of just from inspiring English sources

A mutation of just one gene will cause abnormal cell behavior leading to the synthesis of a dysfunctional protein.

Structural analysis reveals that the substrate peptides are loosely bound within PR active pocket to form a wide contact interface between them, and thus mutation of just single or few residues seems not to influence PR substrate binding considerably.

Such discoveries question the importance of studies of the point mutation of just one peculiar gene.

Mutation of just the two central lysines (K33,34) had almost as strong an effect, whereas mutation of the outer lysines (K20,65) did not greatly affect endocytosis.

However, within a native ISW2, complex mutation of just the SLIDE domain results in only small defects in the affinities for DNA or nucleosomes (Hota et al., 2013).

As stated above, this methodology by Toombs et al., displaying a fairly high classification accuracy when compared to other available methodologies, rely on the random mutation of just two short segments of 19 and 7 amino acids of Sup35, a domain of almost 100 residues with long glutamine and asparagine-rich stretches.

TILLING provides an allelic series of mutations, and is the only method that can focus the search for missense mutations to just part of a protein, such as in a single domain of a multidomain protein.

For example, the immunoglobulin-binding protein A (IbpA) of Histophilus somni contains a direct repeat of two Fic domains, and mutation of IbpA or just the fic domain of IbpA decreased the virulence of this bacteria.

Variation among the four sets of MA lines in terms of mutation spectra was just outside of common significance thresholds (P = 0.07).

The availability of mutations is just one of many factors, some internal and some external, that can determine or block the path to domestication in different species.

The complexity of interactions is remarkable, although one mutation in just one of these genes is enough to destroy the cascade of events leading to healthy cochleas and retinas.