Sentence examples for mutation in codons from inspiring English sources

Of note, Caco-2 cells do not carry mutations in either KRAS or BRAF genes [25] whereas CT26 and HCT116 cells exhibit an activating mutation in codons 12 and 13 respectively of the KRAS proto-oncogene [26], [29].

Patients presenting with "atypical" MEN 2B harboring the germ-line double-point mutation in codons 804 and 904 (V804M and S904C) were also reported.

The 114-bp amplicon was used to screen for KRAS mutation in codons 12 and 13 of 164 sporadic CRC samples.

In three cases it was found that isolate 145 contained the mutation in codons L533P and S540R, whereas isolate 48 contained D516V and S540R.

For KRAS gene exon 2, a specimen was defined as a mutation-positive result if a mutation in codons 12 and 13 was detected by at least either one of the two reference assays.

Using a pre-screening approach in codons 12 13 with high-resolution melting curve analysis (Simi et al, 2008) followed by sequencing, we found 35% cases with a mutation in codons 12 13, in agreement with the literature.

PCR-RFLP results showed that 6755.4.4%) isolates had mutation in codon 315 of katG by SatI endonuclease.

One sequence had a mutation in codon 144, which has previously been reported to give false negative HBsAg results.

One macrofollicular adenoma presented a mutation in codon 201 of the GNAS gene.

Using visual inspection we found two nonsense mutations in codon 35 in ND5 and codon 108 in ND3 in mtAncestor-2 and one frameshift mutation in codon 204 in COX2 in mtAncestor-1.

The most frequently observed mutation was a silent C->T mutation in codon 65 of the pncA gene.