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Exact(7)
There was no distribution difference in ER β cytosolic expression and positive EGFR mutation, even in weak expression group.
This finding was not surprising, given the worldwide low frequency of this mutation, even in severe infections.
We showed that clonal interference impeded the rate of spread of the BoxG18A mutation even in the population in which it was substituted.
However, since we have sequenced only exons 2, 9, 13, we cannot exclude the unlikely possibility of a SDHA mutation even in cases showing SDHA protein expression.
These results demonstrate that the H3K37A mutation, even in the context of normal TORC1 signaling, is capable of significantly impeding Nhp10 binding at specific TORC1-regulated target genes.
2 We fully agree that this will likely be an infrequent mutation, even in the population of dysferlinopathy cases with only one known exonic dysferlin mutation, though it might be recurrent in specific populations.
Similar(53)
Given the proven sensitivity of our techniques we would therefore have expected to detect the hypersensitive ER-α mutation even if present in only a minority of cancer cells or contaminating normal cells.
This work could be extended to properly identify the gene associated to a mutation, even if it appears in the caption of the table, in a column header, and/or as a field in the same row as the mutation.
This advantage was present in patients, having either BRCA 1 (HR 0.20; 95% CI, 0.12 – 0.32), or BRCA 2 (HR 0.21; 95% CI, 0.02 – 1.91) mutations even if in the latter group a small number of patients may affect the strength of evidences.
Michael S. Watson, executive director of the American College of Medical Genetics, said that many mutations even in disease-causing genes do not produce serious or even detectable illness.
From this experiment, it appears that speed-independence is a fragile property that is easily destroyed by random mutations even in cells that are otherwise viable.
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