Sentence examples for mutation assay with from inspiring English sources

The Ames reverse mutation assay with strain YG1042 also demonstrated consistent biological responses, similar to that reported in a previous whole smoke study [29].

This chapter introduces the methods to establish the genetically engineered S. typhimurium tester strain expressing human CYP and reductase (OR) and to describes the procedure of mutation assay with the established S. typhimurium tester strain.

Although not used in this work, it is possible to repeat the mutation assay with a single probe when one doubts the result, for instance when the presumed mutant peak is very small.

Mutation assay with Salmonella typhimurium enabled us to detect various types of mutagens in cooked foods.

Using a standard genotoxicity test battery, Teo et al. (2003) evaluated the activity of MPH in the bacterial reverse mutation assay and mouse lymphoma mammalian mutation assay with and without metabolic activation, and in a bone marrow micronucleus test in male and female CD-1 mice.

High resistance to ciprofloxacin, MIC above 4 μg/mL, linked to the mutated genotype predicted by MAMA-DEG PCR (mismatch amplification mutation assay PCR with degenerated primers) was found frequently among isolates from the different hosts.

A mutation assay system with Chinese hamster lung cells (CHL) using diphtheria toxin resistance as a selective marker has been established.

The five mutations assayed with Tyr-T1-tRNATyr also showed rates of GTP hydrolysis comparable to those of the wild-type protein.

CRISPR/Cas9 -induced indel mutations were detected through mutational assays with T7 endonuclease I and Surveyor nuclease and through direct sequencing of the PCR products.

In the present study, we investigatee the potential genotoxic effects of a water extract of Oryeong-san (ORSE) in three mutagenicity assays (an in vitro bacterial reverse mutation assay (Ames test) with Salmonella typhimurium and Escherichia coli strains, an in vitro mammalian chromosomal aberration test using Chinese hamster lung cells, and an in vivo micronucleus test using ICR mice bone marrow).

Therefore, combining transgenic rodent gene mutation assays 1 with repeated-dose toxicity studies would conform to the 3Rs principle (Replacement, Refinement, and Reduction) of animal use in laboratory experiments.