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Exact(5)
Such mutants would provide important, direct evidence in support of our proposed model.
Therefore, a collection with double transport mutants would provide invaluable information about possible transporters for those drugs not yielding hits.
On the other hand, comparing mutations between AM and AS mutants would provide clues on the causal mutation of mutant phenotypes.
Further studies on in planta interaction using sRNA biosynthetic mutants would provide better understanding of molecular mechanisms behind host-pathogen interaction which in turn useful for developing novel disease control strategies.
18, 19 The hypothesis that vaccination with these HR mutants would provide efficient immunogens resulting in high levels of specific neutralizing antibody, similar to what is seen after infection with WT DV, was tested in this study.
Similar(55)
Nevertheless, the phenotypes of gene deletion mutants relative to those of a mutant pool would provide insight regarding cellular processes having a large growth control under the investigated conditions.
But there is nothing to compare a synthetic effect with, such as another mutant that would provide a longer inter-SPB distance when coupled with a chl4 deletion.
We have not added FISH analysis of rec-8 him-8 double mutants because this would provide limited new insight.
We did not conduct immunohistochemistry for CP, but if increased CP is localized in the RGC layer of mutant animals, it would provide evidence that P4 Chrnb2−/− mice have higher rates of RGC death compared to WT animals.
We speculated based on previous work by others [ 58- 60] that the neor gene might exhibit diminished activity of mutant R49C gene that would provide novel insights into the biology of R49C αA-crystallin in vivo.
We speculated that substitution of the S97 and S247 residues with acidic amino acids Asp and Glu, which have carboxy side chains, would provide CYP199A2 mutants that recognize hydroxy aromatic compounds instead of aromatic carboxylic acids.
Related(20)
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