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The gene disruption mutant was hypersensitive to UV-light (254 nm), mitomycin C and H2O2, indicating that D. discoideum recA is important for survival following exposure to DNA damaging agents.
The cpr5 mutant was hypersensitive to ABA in the seed germination, cotyledon greening and root growth, whereas transgenic plants overexpressing CPR5 were insensitive.
It was also found that the cpr5 mutant was hypersensitive to NDGA and NDGA treatment aggravated the ABA-induced delay in the seed germination and cotyledon greening.
It has been shown that M. tuberculosis ahpC gene could complement the loss of the same gene in Salmonella typhimurium in which the mutant was hypersensitive to reactive nitrogen intermediates [17].
At all concentrations tested, the cpr5-1 mutant was hypersensitive to ABA at both germination and postgerminative growth stages, and the sensitivity occurred in a dosage-dependent manner (Figure 3C, E, G).
While the diploid tho2Δ mutant was hypersensitive (>125-fold greater than WT) to DOX, the isogenic haploid tho2Δ mutant displayed only a modest (5-fold greater than WT DOXX sensitivity.
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dr0615 gene mutant is hypersensitive to H2O2, but only a little to ionizing radiation.
Because an initial analysis indicated that ROM2 is involved in cell growth specifically at high temperature conditions and that the rom2 mutant is hypersensitive at high temperature conditions [7], we further examined the temperature sensitive phenotype related to virulence and cell morphology.
(A ) Ppa-obi-1 mutant is hypersensitive to 0.10% ZTDO compared to wild type PS312 (California).
The abo3 mutant is hypersensitive to ABA in both seedling establishment and seedling growth.
The Arabidopsis atm mutant is hypersensitive to γ-radiation and MMS but not to UV light [ 17].
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