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Exact(6)
Dicer-1 is required for normal development, and the Dcr-1Q1147X mutant is therefore homozygous lethal, but at least in the heterozygous condition it does not affect the viral titers (Fig. 3).
A plausible explanation for the compromised NAD degradation and TRPM2 gating associated with the PARP-dAMD mutant is therefore that PARP-dAMD is unable to recruit appropriate effector proteins via the BRCT domain.
The Cloth-ears mutant is therefore the first evidence that mutation in Scn8a can result in hearing impairment in mice.
Testing this double mutant is therefore critical in resolving the role of USF family of proteins in the circadian system.
The suppression of hsr8-1 developmentphenotypenotype in the soh715hsr8-1 mutant is therefore caused by the deletion of At1g25540, encoding the MED25/PFT1 protein [ 16, 17].
Overall, the predictive value of fly survival time for the fungal burden of any given mutant is, therefore, best for the target organ liver at 7 days after infection.
Similar(54)
The genome of the ptb mutant was therefore re-sequenced, together with its parent strain (ATCC 824 wild type), and shown to possess a frameshift mutation in the thl gene, which perfectly explained the observed phenotype.
Of those, one mutant's growth was temperature-sensitive, and this mutant was therefore chosen for further analysis.
The gns2 mutant was therefore renamed Atelp3-10.
EMSAs with this mutant were therefore performed at 4 °C.
The hyphae of the rsr1Δ mutant were therefore less likely to grow around obstacles and into gaps (Fig. 3D).
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