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Exact(8)
While SNS is phosphorylated on tyrosine residues [36], the ability of Duf 4 phos-flag to only partially rescue the duf, rst mutant, implies that phosphorylation of these sites also contributes to Duf function.
However, the fact that rad51Δ has no effect on hybrid formation in the rnh1Δrnh201Δ mutant implies that alternative mechanisms for hybrid formation, presumably in cis, exist.
The phenotype of the wilty mutant implies that a gene involved in the ABA biosynthesis pathway may be compromised in this mutant.
The presence of an F584S mutation in addition to S531L in the RIF-dependent mutant implies that secondary mutations might contribute to the phenotype of strains that grow better in the presence of RIF; however, this requires formal demonstration.
The fact that most cluster III genes showed some activation under oxic iron-limiting conditions in the oxyR mutant implies that factors other than OxyR are responsible for maximal induction.
Comparison of the folding kinetics of the WT sequence with that of the W8Y mutant implies that the slow (100 μs) step in the folding of the former is tight packing of the side chains to form the native structure.
Similar(52)
Such residual co-localization was evident even for the ire1 ΔKR/Δ-box) mutant, ire1 ΔKR/Δ-box3′ BE-mutanted targetimplyingrs irrespecthat of any cytosolic portion of Ire1.
A phosphopeptide mapping of these two mutants revealed that Ser was not phosphorylated in the Ser343Ala mutant, whereas Ser was normally phosphorylated in the Ser358Ala mutant, implying that Ser is required for Ser phosphorylation and that Ser is the site directly mediating 14-3-3 14-3-3 14-3-3
Furthermore, the three double mutants (Δlsp12, Δlsp13 and Δlsp23), and the triple mutant (Δlsp123) produced WAP-8294A2 at levels similar to that produced by each single mutant, implying that the Lsp proteins do not exert additive effects in regulating WAP-8294A2 biosynthesis.
Dynamic simulations of the wild type and N-terminal H1 deletion mutant implied that Png1p-ΔH1 is more flexible than wild type Png1p.
However, increased cell proliferation did not precede the occurrence of urine flow reduction in the pc mutant, implying that elevated cell proliferation was not the primary phenotype causing cyst formation.
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Justyna Jupowicz-Kozak
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