Sentence examples for mutant coupled with from inspiring English sources

To increase the ee of (S -ECH, the catalyS -ECHs carried outhesing Hhecatalysiscoupled wash epoxide hydrolase mutant and the maximum yield and ee of (S)-Ecarriedhed 91.2% and > 99%.

The lack of the SOS response in the wildtype and the dnaA46 mutant coupled with the demonstration (Figure 4) that the DnaA step in the initiation process had been completed, suggests that a persistent open complex at oriC can also be an inducing signal.

The greatly reduced enzyme activity of the E47A mutant coupled with its altered pH-rate profile was consistent with a role for Glu to act as a base in the catalysis reaction.

The role of Arg242 is unclear, but the higher Km app observed for this mutant, coupled with the mobility of the domain bearing this residue (as revealed by comparison with the apo structure), suggests that interaction between this residue and the substrate cannot be ruled out.

On the basis of the absence of alanine-modified lipid A in the Cys316A mutant, coupled with the fact that low levels of l-alanyl-AlmF are generated by this variant in our in vitro assays, we propose that AlmG displays strict specificity for glycyl-AlmF.

The system reported on here was shown to rapidly prepare HA mutants on cell surface and to allow for easy analysis of the functions of these mutants coupled with easy genetic manipulation of yeast.

Lisso et al. [ 38] used exo T-DNA mutants and EXO overexpression in exo mutants coupled with sucrose and trehalose feeding studies to study the function of EXO.

Thirdly, the significant drop in Bmax for I-CXCL10 binding at the D195N and E196Q mutants, coupled with the relatively poor ability of Cp#1 to displace I-CXCL10, leads us to omit Cp#1 from these experiments.

The extreme severity of fly csp mutants coupled with the unfeasibility of performing high throughput screens in mice suggests that the worm dnj-14 model may be an attractive new platform for chemical genetic screens for neuroprotective factors.

Our measurements of gene conversion in mlh3 Δ mms4 Δ mutants, coupled with previous analyses of recombination intermediates in crossover resolution mutants, are consistent with meiotically induced DSBs forming at wild-type levels in mlh3 Δ mms4 Δ strains [ Table 8 (Argueso et al. 2004; Nishant et al. 2010; Zakharyevich et al. 2012).

This rapid recovery of oviposition in learning and memory mutants, coupled with removing fly heads and inhibiting synaptic transmission in the MB, suggests that maintenance of the depressed oviposition state requires continued neural signaling mediated by a memory component of the brain.