Sentence examples for mutant and demonstrated from inspiring English sources

We subsequently purified the APN-1 from this yeast mutant and demonstrated that it possesses four distinct DNA repair activities.

These results are, again, in agreement with our transcriptome profiling of the ΔrovA mutant and demonstrated that the cell membrane is inadequately constructed in this mutant.

Furthermore, we sequenced the AN gene in the doq-1 mutant and demonstrated a G to A transition at position 509 in the cDNA coding region.

We have constructed the S. oneidensis Δ nagP targeted deletion mutant and demonstrated the loss of its ability to grow on Nag (see additional data file 6).

In vitro studies confirmed the activation of CRAF/MEK/ERK cascade by the kinase-impaired p.Y472C mutant and demonstrated dasatinib-induced senescence and apoptosis in lung cancer cells expressing kinase-impaired p.G466V mutant, but not in cell lines with kinase-activated BRAF mutants.

In this study, we identify gna-2 qa705 gna-2 qa705 Pod mutast, anovelmonstrate that eggshell chitin and two functionally redundant chitin-binding Podteins, CEJ-1 and B0280.5, are essential for error-free segregation at mutants, for extrusion of the polandbodemonstrater SPCC associathat with theggshell.

Together, these data identify ERβ as a candidate effector of BPA action in prostate cancer cells expressing the AR-T877A mutant and demonstrate that BPA induces a unique transcriptional signature in prostate cancer cells that may be influenced by AR status.

In addition, we have applied the Amplifluor® genotyping to the mapping of C. elegans mutants and demonstrated that it is possible to link a C. elegans mutation to 5 8 Mb sub-chromosomal regions using only 9 SNPs.

Early studies also used plasmid-based expression of nup FG domain deletion (Δ FG) alleles to complement lethal chromosomal nup null mutants, and demonstrated that most individual FG domains can be removed with no loss in cell viability (Nehrbass et al. 1990; Grandi et al. 1995; Iovine et al. 1995; Del Priore et al. 1997).

Through the transient expression of mitoTALENs, we achieved a remarkable reduction in mutant mtDNA and demonstrated the functional metabolic rescue of MiPSCs and derived NPCs.

Using a gradient PCR, we identified the Tc for each mutant template and demonstrated that it was correlated to the primer's Tm.