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Muscle cells respond to exercise by pumping out a variety of substances that result in larger, stronger muscles.
The basal lamina of these fibers often appeared irregular, suggesting that the melanoma cells disrupt the extra-cellular matrix of the myofiber or that neighboring muscle cells respond to the presence of melanoma cells and alter their ECM composition (Figure 3).
Striated muscle cells respond to changing functional requirements by a coordinated set of adaptations.
In addition to biochemical stimuli, muscle cells respond to biomechanical stimuli by modulating protein expression through activation of signaling pathways [ 89, 90].
We have demonstrated by comparison of a number of parameters that A-10 vascular smooth muscle cells respond similarly on thin films of collagen as they do on thick hydrogels of collagen [ 18].
In the aortic wall, vascular smooth muscle cells respond to biomechanical factors both directly through the exposure to cyclic stretch in response to the pulsatile pressure, and indirectly through mediators convected through the aortic wall with the transmural interstitial flow.
Similar(54)
How the muscle cell responds to mtDNA depletion, impaired oxidative phosphorylation and severe loss of energy production and how these mechanisms differ between MDS and other mitochondrial myopathies is not well understood.
In normal muscle these cells respond to regenerative cues such as injury or exercise to provide new myonuclei for the homeostasis, hypertrophy or repair of muscle fibres.
This overexpression was shown to cause significant muscle atrophy due a block in the differentiation of muscle progenitor cells responding to injury signals emanating from the tumor.
Potentially, the disruption of the basement membrane due to the injury or attrition of the myofibers, differentiation of satellite cells along myogenic lineage, and/or extracellular matrix - based activation of FGF-2 for binding to its receptors might be required for the induction of FGF-2 signaling in the muscle stem cells responding to tissue damage.
The latter depends on the ability of smooth muscle cells to respond to nitric oxide and therefore measures the integrity of arterial media.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com