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Given the incontrovertible role of some ADAMTS enzymes, and in particular the proteoglycanases during murine embryonic development, it is likely that similar and additional roles exist in the developing zebrafish embryo.
Cx36 is expressed dynamically during murine embryonic development and it is switched on earlier than other Cxs.
In order to study the linker histone function during early murine embryonic development, three isoforms had to be knocked out due to the high level of redundancy [5], [31].
These findings suggest stage-specific roles of CD98hc in murine embryonic development.
Murine embryonic development was accessed via in situ hybridization, measurement of skeletal parameters and micromass differentiation of mesenchymal cells.
During murine embryonic development, Ifitm1 is expressed in the extraembryonic and embryonic mesoderm until the mesoderm differentiates [ 14, 15].
Similar(46)
This up-regulation, unlike that experimentally induced during murine embryonic and fetal development, does not compromise animal viability, and thus dosage effects must not be critical during postnatal development.
Although conventional Cdh1 knockout was of little immediate value for elucidating the tumor suppressor function of E-cadherin, it inspired many decisive studies on the important roles of E-cadherin in murine embryonic stem cells and embryonic development [ 56].
In conclusion, we have identified an essential role for FKBPL in murine embryonic and zebrafish vascular development.
The placenta-specific 1 (PLAC1) gene encodes a membrane-associated protein which is selectively expressed in the placental syncytiotrophoblast and in murine fetal tissues during embryonic development.
A similar pattern was reported by Parker-Katiraee et al. (2008), who found that PON1 expression in murine liver tissue increased during embryonic development in an allele-specific manner.
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