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Exact(6)
A pathway analysis was conducted to take into account the joint effects of multiple variants to complement the single variant analysis for disease susceptibility.
We found multiple variants to be associated with systolic blood pressure, SBP (7/28 tSNPs min-p = 0.0005), diastolic blood pressure, DBP (7/28 tSNPs min-p = 0.002) and 24 hour urinary potassium excretion (10/28 tSNPs min-p = 0.0004).
The contribution of the presented multiple variants to the immune response against T. gondii seems to be possible.
VAAST [ 55, 56] is another technique that aggregates information from multiple variants to identify the genes and variants underlying genetic disease.
Statistical corrections to the read counts are required when the density of local variations allows multiple variants to fall in the same read or read-pair.
We refer to this alternative approach as 'condition-specific codon optimization.' Furthermore, we utilize a probabilistic method that incorporates codon context into optimized gene design and thus results in multiple variants to be tested rather than a singular design.
Similar(53)
Parametric modelling offers dynamic control over geometry and components, allowing the designer to assess multiple variants at the same time.
Uniaxial tensile test on sample A with prismatic texture along the tensile axis showed lower yield strength but higher ductility and twin activity with multiple variants compared to orientation B with basal texture along the tensile axis.
Assembly of both maxicircles was complicated by the presence of multiple variants due to apparent intrastrain heterogeneity of the maxicircle population.
One possibility is that multiple variants contribute to this multisystemic phenotype, as has been reported in other exome sequencing studies of rare disease (5).
Tags with matches to multiple variants were attributed to the most common variant, so that each tag counted only once.
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