Sentence examples for multiple mutants to from inspiring English sources

The authors used whole seedling protein preparations for comparisons between wild type and multiple mutants to show that PP2Cs control the activity of OST1 but not of CPKs and the interdependence of the Ca2+ dependent and independent pathway.

The problem is that GEMMs are ridiculously slow and expensive to produce, especially in the context of cancer, as you have to intercross multiple mutants to get a configuration that can replicate the complexity of the human tumor.

This is particularly useful when the genetic backgrounds of multiple mutants need to be maintained in a pure background.

However, MD simulations are very computationally expensive to converge and it is not immediately obvious how to compare multiple mutant simulations to one another in a statistically significant and efficient manner.

In this study we applied proteochemometrics modeling to analyze susceptibilities of multiple HIV mutants to eight clinically used nucleoside/nucleotide analog reverse transcriptase inhibitors.

In this study, we investigated the contribution of each particular disulfide to the folding, stability and function of LCI by constructing a series of single and multiple mutants lacking one to four disulfide bonds.

Instead, they have relied on the study of single or multiple mutant combinations to reveal the generation of phenotypic patterns (e.g. [ 1]).

In contrast with transmissible spongiform encephalopathies, animal models of common human neurodegenerative diseases often require the over-expression of multiple mutant transgenes to incompletely mirror certain features of pathogenesis.

By contrast, the multiple mutants were up to 8-fold less efficient than the recombinant wild-type dalcochinase, and displayed primarily antagonistic interactions between these residues.

As a consequence, this vector will be a highly valuable means for the rapid generation of single or multiple mutants remaining sensitive to the most reliable selection markers Blasticidin S and neomycin.

Our streamlined system for knockout-construction along with the convenient and easy to use method to create multiple mutants by crossing can serve as a starting point for large scale functional analysis studies aimed to uncover the hidden treasures of the biotechnological workhorse T. reesei.