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These structural features are expected to have a relationship to properties arising from intermolecular interactions and may also function to provide discrimination among multiple structural classes.
Evolutionarily it seems that a single early eIF4E gene has undergone multiple gene duplications generating multiple structural classes.
Evolutionarily it seems that a single early eIF4E gene has undergone multiple gene duplications generating multiple structural classes, such that it is no longer possible to predict function from the primary amino acid sequence of an eIF4E-family member.
The discovery of multiple structural classes of compounds that modulate gamma-secretase activity, instead of inhibiting it, offers the potential promise of avoiding the mechanism-based adverse events observed with gamma-secretase inhibitors.
Throughout the eukaryotic domain, a series of eIF4E gene duplications has led to the generation of a family of proteins with multiple structural classes and in some cases subclasses within a given organism [ 30, 33, 35].
This protein complex, which assists the folding of a large number of proteins of multiple structural classes and complex topologies (Thulasiraman et al., 1999; Dekker et al., 2008; Yam et al., 2008), could constitute a metabolic bottleneck in Antarctic notothenioid cells should its function be compromised by elevated temperature.
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PreSSAPro predicts the secondary structure according to the right protein class, if known, or gives a multiple prediction with reference to the different structural classes.
In eukaryotes, the cardiolipins (CL), a class of mitochondrion-specific anionic phospholipids, play multiple structural and functional roles in bioenergetics, mitochondrial signaling, and cellular fate pathways.
The wildfire has damaged or destroyed over 150 structures, and firefighters continue to battle multiple structural fires.
This is a risky stock, facing multiple structural issues and considerable fixed costs.
This paper proposes a novel approach which combines an industry foundation classes (IFC -based Unified Information Model with a number of algorithms to enhance the interoperability: (a) between architectural and structural models, and (b) among multiple structural analysis models (bidirectional conversion or round tripping).
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several structural classes
numerous structural classes
multiple functional classes
various structural classes
many structural classes
multiple structural functions
multiple phenotypic classes
multiple structural schemas
multiple structural modifications
multiple structural domains
multiple structural determinants
multiple structural issues
multiple structural STs
multiple structural features
multiple structural requirements
multiple structural reforms
multiple structural changes
multiple ordinal classes
multiple structural units
multiple structural consultants
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