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Indeed, it is difficult and time-consuming to obtain such labels in the protein function prediction field as each protein instance may has multiple functional classes simultaneously.
The high proportion of genes detected in the main olfactory organ, the antennae, is consistent with the presence of multiple functional classes of sensilla recently described in Cx. quinquefasciatus [37].
The complete mapping of olfactory sensilla on the antennae [12], [13] and maxillary palps [14] of the Southern house mosquito Culex pipiens quinquefasciatus ( = Cx. quinquefasciatus) led to the identification of multiple functional classes of sensilla.
Ontology analysis of genes associated with endogenous c-Myc in ES cells indicates, as expected from previous studies, that they fall into multiple functional classes involving growth, metabolism, cell signaling pathways, cell cycle progression, and apoptosis.
The 72 upregulated and 12 downregulated candidate genes described above were categorized into multiple functional classes of proteins (supplementary material Table S1).
We list predicted functional classes for ten genes with most predicted functional terms in Table 6, these genes were unknown in April 2007, but they were annotated with one or multiple functional classes in December 2008.
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When multiple best hits pointed to different functional classes, a hit of the spacer was counted once for each class.
We propose that the six clades of GFP-like proteins may represent several functional classes of proteins with multiple variants in each class.
A single compound may have multiple functional groups, thus, it may be part of multiple chemical classes.
The annotated SLiMDom dataset reveals that many globular domain classes bind to multiple ELM classes (156 ELM classes annotated to 85 globular domain functional classes).
Looking more broadly over multiple lineages, it will be interesting to see which structural and functional classes of RNA are differentially conserved within and between lineages and which are subject to stabilizing, neutral, or even positive, selective pressures.
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multiple functional groups
multiple functional queens
multiple functional layers
multiple functional properties
multiple functional copies
multiple functional STs
multiple ordinal classes
multiple functional proteins
multiple functional manifestations
multiple functional processes
multiple functional advantages
multiple functional peripheries
multiple functional regions
multiple functional structures
multiple functional forms
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