Sentence examples for multiple steps by from inspiring English sources

miR-31 prevents metastasis at multiple steps by inhibiting the expression of prometastatic genes.

miRNAs can modulate a wide variety of targets, which endowed the supposition that a single miRNA might regulate cancer progression in multiple steps by targeting numerous genes.

The TGFβ signaling pathway can be regulated at multiple steps by various molecular regulatory mechanisms including ubiquitination of pathway molecules [ 17].

MiR-31, which is expressed in normal breast cells and was recently shown to prevent metastasis at multiple steps by inhibiting the expression of prometastatic genes [ 27], was observed to be downregulated in BC datasets.

The scenario-reviewer role is mostly supported by the graphical nature of the scenario and the ability to use hierarchical arrangement of scenarios (i.e., a node may expand into multiple steps by using subflows).

miR-31 was recently shown to prevent metastasis at multiple steps by inhibiting the expression of prometastatic genes [ 61]. miR-31 is expressed in normal breast cells and its abundance was shown to be dependent on the metastatic state of the tumor.

We believe that the presence of this 2D layer might be a general feature in the samples grown with our multiple steps DE, by observing growth interruption times.

ES cell-based targeting technology enables introduction of subtle genomic modifications, but it is a lengthy process involving multiple steps (reviewed by Menke 2013).

While the quinone ring is derived from tyrosine or phenylalanine, the isoprenoid side chain is produced by addition of isopentenyl diphosphate molecules to farnesyl diphosphate or geranylgeranyl diphosphate in multiple steps catalyzed by polyprenyl diphosphate synthase (PDSS1 PDSS2).

The unique fragmentation consisting of multiple steps is induced by a cyclization reaction of b ions, the mechanism of which has been probed by experiments of N-acetylation, MSn, rearranged-ion design, and activation-time adjustment.

These findings indicate that miR-124 suppresses multiple steps of metastasis by diverse mechanisms in breast cancer cells and suggest a potential application of miR-124 in breast cancer treatment.