Sentence examples for multiple regulatory circuits from inspiring English sources

Regulation of iron homeostasis genes has been shown to be complex and dependent on multiple regulatory circuits.

The genome is 60,099 bp, consisting of at least 74 genes and multiple regulatory circuits controlled by 7 transcriptional regulators, including four global regulators KorA, KorB, KorC and TrbA [ 13].

Advanced cancer is a multifactorial disease that accumulates many genetic and epigenetic alterations affecting multiple distinct regulatory circuits within cells.

It is worth noting that these two bacterial species produce multiple AHL signals and have multiple complete QS regulatory circuits [ 42, 46].

Meaningful responses to single targeted agents are, however, rare and often transient in nature. 2 At the cellular level, robustness to drug intervention arises from the multiple redundancies and feedback regulatory circuits embedded in the oncogenic pathways driving cancer cell growth and survival.

These data suggest that aberrant expression of miRNAs may modulate the activity of particular transcription factors and alter gene regulatory circuits at multiple hierarchical levels leading to the disease phenotype.

We propose that the apparent requirement for multiple, redundant sRNAs in many bacterial regulatory circuits is coupled to their stoichiometric mode of action.

Multiple, distinct, but partly redundant, pathways and regulatory circuits have come together to reinforce each other, selected for the addition of robustness and resistance to noise.