Sentence examples for multiple neuropsychiatric disorders from inspiring English sources

Due to its role in clearing serotonin from the synaptic cleft, SERT plays a central role in neurotransmission and a broad role in brain activity making it a sought after therapeutic target of multiple neuropsychiatric disorders [170].

The two most studied components of the serotonergic system that have come into the spotlight in determining susceptibility to migraine as well as multiple neuropsychiatric disorders are the serotonin transporter (SERT, also known as SLC6A4), which reuptakes serotonin from the synapse, and monoamine oxidase A (MAOA), an important enzyme that degrades serotonin and metabolizes triptans [23].

Downregulation of D2Rs has been implicated in the pathology of multiple neuropsychiatric disorders, and more than 50 drugs that target members of the dopamine receptor family have been developed as pharmacological interventions.

ReHo is a promising index of human brain function that has been applied to multiple neuropsychiatric disorders [ 2, 12– 12].

Common genetic variation and rare mutations in genes encoding calcium channel subunits have pleiotropic effects on risk for multiple neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia.

Although there are hundreds of standardized neurocognitive tests available,[ 43] it is important to consider the adoption of a more uniform battery when taking into account the similarities and differences seen among multiple neuropsychiatric disorders.

Disrupted dopamine (DA) signaling is believed to contribute to the core features of multiple neuropsychiatric and neurodegenerative disorders.

So could brain gene synchrony also integrate the multiple factors engaged in neuropsychiatric disorders and reveal underlying pathologies?

In clinical diagnostics, both array comparative genomic hybridization (array CGH) and single nucleotide polymorphism (SNP) genotyping have proven to be powerful genomic technologies utilized for the evaluation of developmental delay, multiple congenital anomalies, and neuropsychiatric disorders.

Both array CGH and SNP genotyping are routinely utilized by clinicians for the evaluation of patients with developmental delay (DD /intellectual disability (ID), multiple congenital anomalies (MCA), and neuropsychiatric disorders.

Human endogenous retroviruses (HERVs) entered the human genome through repeated integration events over the past 2 30 million years [1], [2] and have been implicated in both health and disease including neuropsychiatric disorders such as multiple sclerosis (MS) and schizophrenia [3], [4].