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Mice carrying a hepatocyte-specific disruption of the frataxin gene develop multiple liver tumours for unresolved reasons.
The IFN- α/5-FU therapy for remnant multiple liver tumours was applied postoperatively, as described previously (Ota et al, 2005; Nagano et al, 2007a).
Finally, multiple liver tumours, morphologically similar to those generated using a conditional SB11 screen for hepatocellular carcinoma [ 27], were observed in 19 mutagenised Ptch+/- mice but not in predisposition controls.
In total, 30 patients with multiple liver tumours spreading to both lobes with tumour thrombi in the major branches of the portal vein, underwent palliative reduction surgery at the Osaka University Hospital as described in our earlier report (Nagano et al, 2007a).
All patients had multiple liver tumours in both lobes and tumour thrombi in the main trunk of the portal vein, and each underwent palliative reduction surgery with tumour thrombectomy of the main trunk of the portal vein at the Osaka University Hospital between 1999 and 2004.
Similar(55)
The IFN- α/5-FU therapy for the remnant multiple liver tumour was applied postoperatively, as described previously (Ota et al, 2005; Nagano et al, 2007a).
Compound Alb Cre, Mst1/Mst2 mutant mice show marked liver enlargement at 4 5 weeks age and require euthanisation by 4 5 months because of multiple large liver tumours.
7-Methylbenz(a)anthracene itself was the most actively tumorigenic of the compounds studied, giving rise to subcutaneous sarcomata at the site of injection, and multiple lung tumours and liver tumours.
Lack of radiological evidence of a gross tumour and the presence of multiple liver cysts complicated the preoperative tumour diagnosis, thereby making surgical management difficult.
Among two patients with PR, one patient had a BRAF-mutant tumour with multiple liver metastases from an ascending colon cancer.
Liver and tumour blood flow has been studied in 30 patients with multiple liver metastases and in 14 patients with solitary liver tumours by means of dynamic hepatic scintigraphy.
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