Sentence examples for multiple isoforms which from inspiring English sources

Of the four MEF2 members, all can be tissue-specific alternatively spliced, producing multiple isoforms which have significant functional differences [1] [4].

In general, the alternative splicing of FGFRs generates multiple isoforms, which are selectively expressed in different types of cancer.

Actin generally occurs in multiple isoforms which are expressed in a tissue- and development-specific manner [ 28].

Several of these genes had multiple isoforms, which showed differences in bivalency at their discrete promoters, while all isoforms were type-specific by their expression.

ELP is secreted in milk in multiple isoforms, which include an ~8 kDa peptide and a heavily N-glycosylated protein (~16 kDa) [ 25].

Both type IV collagens and laminins have multiple isoforms, which creates an even greater diversity of BM composition in various organs.

Our present knowledge of P450 enzyme-catalyzed herbicide resistance of plants supports the existence of multiple P450 isoforms, which are herbicide or pesticide specific in nature.

The best studied example, the 5-HT2C receptor, is dynamically edited at five positions (A to E) in exon V, leading to multiple receptor isoforms, which differ in constitutive activity and intracellular signal transduction efficacy, thereby modulating the strength of 5-HT neurotransmission [43], [51], [52].

Most multi-exon genes can encode multiple protein isoforms which often have different functions and can be disease-related.

The p53-related p63 gene encodes multiple protein isoforms, which are involved in a variety of biological activities.

Genes can choose different sets of splice sites to produce multiple transcript isoforms, which further increases the complexity of splicing regulation.