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Exact(6)
The pulse energy is determined, coincident events are detected and multiple hits within one matrix can be identified.
Genomic regions with multiple hits within single genes were further investigated using a pairwise comparison approach based on sliding windows.
We found that this particular choice of cutoff identifies functional matches for a significant proportion of proteins across two species whilst keeping multiple hits within reasonable limits.
In the field of endometriosis, it has been proposed that the condition results from a series of multiple hits within target genes and gene expression microarray studies have identified a number of candidate gene families that may be differentially regulated.
It has been proposed that endometriosis results from a series of multiple hits within target genes, in a mechanism similar to the development of cancer (Bischoff and Simpson, 2004).
Identification of centromeres was done by searching with fuzznuc from the Emboss suite [ 70], for sequences homologous to S. cerevisiae consensus centromere sequence, ie "[AG]TCA[TC][AG]TG[AC][TC]N 73,167 G[GT]N 7,15 TTCCGAA" [ 75], and by manually checking for conservation of synteny in case of multiple hits within a single scaffold.
Similar(54)
For about a half of them (95,382 tags), all of their multiple hits were mapped within Alu elements while for 80% of them (146,477 tags) more than 85% of their multiple hits overlapped with Alu elements.
A locus was assigned to a specific location in the chicken genome if (i) it provided a unique hit at E ≤ 1e-10, or (ii) it provided multiple hits at E ≤ 1e-10 and within the hits the best hit had an E value at least 10 decimal places lower than the next best hit (see [ 12]).
The distance between humans and chimps is significantly less than predicted from the rate of substitution observed within humans and correction for multiple hits under uniform rate model is not capable of explaining the difference.
Alignments were restricted to 5 hits and, aiming to identify molecules most likely to represent a miRNA, multiple hits were only considered when representing different positions within of a single miRNA family.
Our implementation does assume equal mutations rates across a given class of sites within a locus, which may underestimate the true number of multiple hits.
Related(20)
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