Sentence examples for multiple genes located from inspiring English sources

Finally, it is likely that multiple genes located on different chromosomes may influence ethanol consumption and this may contribute to differential correlations between this trait and DOC suppression by dexamethasone.

However, these studies do not account for the effect of multiple genes located within the 11q13.3 amplicon.

6– 16 In 1986, Schmickel 3 first described contiguous gene syndromes (CGS) as involvement of multiple genes located in close proximity to each other on a chromosome.

Additionally, we observed a striking, statistically significant tendency for individual disease phenotypes to be associated with multiple genes located within a single CNV region, a phenomenon that we denote as pheno-clustering.

To further study the gene space and especially the genes clustered in islands in more detail, we considered gene islands as multiple genes located on the same BAC or overlapping BACs, i.e. separated by less than 150 kb.

The authors also observed a striking and statistically significant tendency for individual disease phenotypes to be associated with multiple genes located within a single CNV region, a phenomenon that they denote as 'pheno-clustering'.

In this study, we developed a set of four real-time PCR assays to detect the presence or absence of multiple virulence genes located within this region.

Multiple Hox genes located in tightly linked clusters have been identified in all animal phyla examined, with the archetypical chordate cluster having 14 genes (Hox1 Hox14) [ 3].

Other fish species also have multiple CYP3 genes located in this region (e.g. four in stickleback and one in fugu), and chickens appear to have two homologs at that locus.

A large number of cancers lose all, or nearly all of 8p, potentially suggesting the presence of tumour suppressor loci, while the occurrence of specific rearrangements on distal 8p supports the theory that there are multiple cancer genes located on 8p.

On the other hand, expression differences have been detected in multiple-copy genes located within the SDs at the inversion breakpoints (e.g. LRRC37A and A4 in 17q21.31, or EIF3C and EIF3CL in 16p11) or in gene families with copies located both within and outside the inverted region (e.g. genes SULTA1, SULTA2 and SULTA4 in 16p11) [ 85, 105].