Sentence examples for multiple cleavages of from inspiring English sources

For a target, multiple cleavages of different categories can be detected because many sRNAs can bind to the same target mRNA.

Other findings also support the hypothesis that HSV-1 induces multiple cleavages of APP, including some that are produced by caspase 3-like enzymes.

We found that infection of SH-SY5Y human neuroblastoma cells and rat cortical neurons is followed by multiple cleavages of APP, which result in the intra- and/or extra-cellular accumulation of various neurotoxic species.

The multiple cleavages of APP that occur in infected cells are produced in part by known components of the amyloidogenic APP processing pathway, i.e., host-cell β-secretase, γ-secretase, and caspase-3-like enzymes.

This information mainly related to multiple cleavages of the hexoside moiety (initially cross-ring cleavage), which are characteristic of C-glucosides (loss of 90, 120, and 148 Da).

Adler and Hajduk [49] suggest that multiple cleavages upstream of the expected ES could involve improper assembly of the exogenous mRNA/gRNA with the purified editing complexes.

Features such as the presence of multiple cleavage sites, distribution of poly(A) signal variants and nucleotide composition of flanking regions were reported to be similar in human and mouse [ 4].

Our data indicate that this complex process of multiple cleavage results in the accumulation of OPA1 oligomer and in the inhibition of cytochrome c release and cell death.

Western blot analyses of the Notch receptor in different tissues, developmental stages and species have long established the existence of multiple cleavage products (e.g. [18]) The pattern revealed by these analyses is variable and can differ both qualitatively and quantitatively, depending on the protein source.

In any event, our overall result is clear: falcipain-2 and falcipain-3 are capable of rapid hydrolysis of hemoglobin at multiple cleavage sites.

Neutral endopeptidase (NEP) is also responsible for a significant proportion of GLP-1 degradation, acting at multiple cleavage sites [ 46], to form of further fragments including GLP-1 (28 36) and (32 36) that have been hypothesized to have potential activity at the mitochondria [ 47, 48].