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The advantage of our study is that it involves a large database from multiple centers with systematic collection of data.
Further prospective studies conducted in multiple centers with larger samples are necessary to appraise the clinical usefulness of the revised CLSI breakpoints.
Exploratory studies in small numbers of mice are conducted in single laboratories rather than multiple centers, with few exceptions (Sarikonda et al., 2013).
Kim Pruitt described the Consensus Coding Sequence (CCDS) project, is a collaboration between multiple centers with a goal of producing a set of high-quality protein coding region annotations for the human and mouse reference genome assemblies (12).
The primary concern with this analysis is the comparison of a series of patients treated at a single center with a highly protocolized approach to transfusion against a registry-based cohort of patients from multiple centers with no standardized protocol.
We acknowledged in our paper that there are limitations to the comparison of patients treated in one center according to a protocol with those from multiple centers with no standardized protocol.
Similar(51)
The calculation of the ICC can easily be programmed and the mechanism has wide applicability, not just to randomized controlled trials but to any study with multiple centers or with multiple observers in a single-center study.
The calculation of the ICC can easily be programmed and the mechanism has wide applicability, not just to cluster randomized controlled trials but to any study with multiple centers or with multiple observers.
Although both large in scale and validated, prospective studies at multiple centers and with heterogeneous populations are needed in the future to further refine the model.
However, since glycemic control was achieved in ADVANCE across multiple centers worldwide with relatively few side effects, this level of glycemic control appears to be both practical and provides useful clinical benefit.
Adult patients with recent-onset type 1 diabetes (n = 53), latent autoimmune diabetes in adults (LADA) (n = 250), and type 2 diabetes (n = 285) from multiple centers were compared with normal subjects (n = 196).
Related(20)
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