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Until recently, there has been much less clinical and research focus on identification and management of upper extremity deep venous thromboses (UEDVTs) than deep venous thromboses (DVTs) of the lower extremity.

Earlier this year the chairman of the Cancer Drugs Fund, Prof Peter Clark wrote: "While the Cancer Drugs Fund currently funds drugs of good benefit to patients, it also includes a minority drugs with much less clinical value.

There is a significant burden of disease associated with major depression, and although depression during and following pregnancy occurs at a frequency similar to preeclampsia (5-85-8%nd preterm birth (11%), it receives much less clinical attention.

Multivariate analysis showed that only the addition of haemoglobin levels could improve upon this and the improvement, though statistically significant (P = 0.006), appeared to be of much less clinical value.

While there is much less clinical data, most of the more rare mutations, KIT exons 13 and 17, and PDGFRα exons 12 and 14, are sensitive to imatinib in vitro [ 9].

However, until quantities or at least presence/absence values are given to nodes in healthy vs. cancer states, I don't feel that it is a reliable measure that can be used in the biological, much less clinical, interpretation of signaling or protein-protein interaction networks.

Similar(54)

However, to date these efforts have been less than successful in identifying clear hypotheses from the mouse models that can be easily translated into the clinic, much less into clinical trials.

Much work is needed before the exact nature of estrogen's role in the stress response will be fully understood, much less yield clinical applications.

Community twin samples are very useful for the study of subclinical traits across the continuum but much less for clinical disorders as ASD.

Noteworthy, the most prominent intrinsically-resistant bacteria have an environmental (non-clinical) origin, in habitats that are much less likely than clinical settings to present intense antibiotic selective pressure.

77 78 Efforts to enforce and encourage registration of other types of research have progressed much less than for clinical trial research, but observational studies can be registered at most clinical trial registries, and a register for systematic reviews has also been established.

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