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Comparisons of measured to simulated PV output of the mouse show that also in practice, simulation accuracies can be very high.

Studies in the mouse show that inbred strains differ significantly in wound healing rates, indicating that in mammals there are genetic factors contributing to this trait [4], [5], [6], [7].

Furthermore, studies in the nonobese diabetic (NOD) mouse show that 1,25(OH)2D3 reduces the incidence of insulitis and diabetes (14).

Our analysis of CNVs in horses and cattle using array comparative genomic hybridization (Doan et al., unpublished studies), as well as studies in the human and mouse show that large (Mb) deletions are common variants in the genome [ 21- 24].

In vivo experiments in mouse show that knocking out EphB affects the direction of interstitial branching from the RGC axon shafts along the mediolateral axis, and suggests that the EphB ephrin-B intEphB ephrin-Bbe attractinteractions et al., 2002).

(A ) Immunostaining of Nrp1 (green) in the P7 cerebellum of wild type and Nrp1/2 DKO mouse show that Nrp1 was specifically knocked out from GNP cells in EGL and parallel fibers in ML, but remains in blood vessels.

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Studies with mice show that administration of ethanol to males alters the epigenetic signatures in the brains of their offspring.

Analyses of Asxl2−/− mice show that Asxl2 has an important role in animal survival and growth.

In vivo studies in ICR and KKAy mice showed that administration of this compound resulted in decreased blood glucose in these mice after an oral glucose challenge.

Mechanistic analysis with gene-targeted mice showed that interleukin-5 was required for esophageal eosinophilia and that interleukin-4, interleukin-13, and STAT6 contributed to a lesser extent.

Studies in B-cell-deficient mice showed that protective immunity to Salmonella strongly depends on B cells [27].

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