Sentence examples for mouse sepsis models from inspiring English sources

Here, we report a detailed assessment of the cardiovascular, metabolic and biochemical phenotypes in long-term rat and mouse sepsis models with similar mortality.

In sepsis patients, extracellular ATP release in PMNs was elevated on days 0 1, corroborating our previous work in mouse sepsis models, wherein plasma ATP levels were elevated and contributed to PMN activation [7].

Together, these findings are consistent with the notion that MMP-1a released from the endothelium of endotoxemic mice contributes to the mortality observed in the mouse sepsis models.

We found that Smaducin-6 had a significant therapeutic efficacy in mouse sepsis models: cecal-ligation puncture (cecal-ligation punctureduCLP -induced

As MMP-Inh-1 has shown inhibitory effects on other collagenases (Odake et al, 1994), one cannot completely rule out that other collagenases are playing a role in the mouse sepsis models.

Here, we demonstrate that this membrane-tethered Smad6-derived peptide, Smaducin-6, had therapeutic efficacy in mouse sepsis models: cecal-ligation puncture (cecal-ligation punctureduCLP -inducedy inhibiting CLP -inducedrm and apoptosis while enhancing neutrophil migration and bacterial clearance.

The study was designed to investigate whether thio-Cl-IB-MECA has an anti-inflammatory potential in mouse macrophage RAW 264.7 cells and mouse sepsis model in vivo.

Therefore, the clinical manifestations of LPS-induced gerbil model were apparently similar to that of C57BL/6 mouse sepsis model [9].

After LPS-treatment, the clinical manifestations of Mongolian gerbil model were apparently similar to that of C57BL/6 mouse sepsis model.

Furthermore, 10C3 showed in vivo activity when it rescued LPS-induced lethality in a mouse sepsis model (Fig. 1D).

The virulence of Δstp1 and Δstk1 mutants was compared with WT using the mouse sepsis model of infection described previously [69].