Sentence examples for mouse sepsis model from inspiring English sources

The study was designed to investigate whether thio-Cl-IB-MECA has an anti-inflammatory potential in mouse macrophage RAW 264.7 cells and mouse sepsis model in vivo.

Furthermore, 10C3 showed in vivo activity when it rescued LPS-induced lethality in a mouse sepsis model (Fig. 1D).

Therefore, the clinical manifestations of LPS-induced gerbil model were apparently similar to that of C57BL/6 mouse sepsis model [9].

The virulence of Δstp1 and Δstk1 mutants was compared with WT using the mouse sepsis model of infection described previously [69].

After LPS-treatment, the clinical manifestations of Mongolian gerbil model were apparently similar to that of C57BL/6 mouse sepsis model.

As expected, the control strain with the transposon Tn5EZ insertion in purA was unable to grow in the absence of exogenous purines (Fig. S2) and was also avirulent in the mouse sepsis model of infection (data not shown).

Here, we report a detailed assessment of the cardiovascular, metabolic and biochemical phenotypes in long-term rat and mouse sepsis models with similar mortality.

In sepsis patients, extracellular ATP release in PMNs was elevated on days 0 1, corroborating our previous work in mouse sepsis models, wherein plasma ATP levels were elevated and contributed to PMN activation [7].

We found that Smaducin-6 had a significant therapeutic efficacy in mouse sepsis models: cecal-ligation puncture (cecal-ligation punctureduCLP -induced

Together, these findings are consistent with the notion that MMP-1a released from the endothelium of endotoxemic mice contributes to the mortality observed in the mouse sepsis models.

As MMP-Inh-1 has shown inhibitory effects on other collagenases (Odake et al, 1994), one cannot completely rule out that other collagenases are playing a role in the mouse sepsis models.