Sentence examples for mouse resources such from inspiring English sources

However, even with the emergence of large-scale knockout mouse resources, such as those of the International Knockout Mouse Consortium (http://www.knockoutmouse.org/), generation of such mutants using embryonic stem (ES) cells may still require substantial time and resources.

Genetic diversity is a crucial component when assessing clinical relevance thus leading to the development of genetically diverse mouse resources such as the Collaborative Cross (CC) [ 19].

An understanding of AS has also proven important for the production of large-scale knockout mouse resources, such as those generated by the EUCOMM and KOMP programs (50).

New mouse resources, such as outbred stocks and advanced intercrosses, have been put to use to facilitate QTL mapping, and the first studies have reported breathtaking results on the number of QTLs and interactions between genes and environment [ 87, 88].

A number of links are provided to selected external resources such as Mouse Genome Informatics [ 17], EntrezGene and the Online Medelian Inheritance in Man (OMIM) databases [ 18] and Kyoto Encyclopedia of Genes and Genomes (KEGG) [ 19] that allows users to access genetic, phenotypic and functional information for genes of interest (see External links below).

This is particularly the case for material resources such as cryopreserved mouse lines, for which rederivation and shipping costs are substantial.

The International Protein Index (29) was used to match Entrez Gene identifiers with entries from other external resources, such as the Mouse Genome Database (MGD; 30) and the Zebrafish Information Network (ZFIN; 31), where possible.

The GUDMAP ontology is currently being incorporated into the existing EMAP ontology, which is used by other resources such as the mouse Gene Expression Database (GXD) (Smith et al., 2007) and EMAGE (Richardson et al., 2010).

Rajendran hopes Matters can also help level the playing field for researchers in poorer areas, who may lack resources such as antibodies and mouse models, "but can still make good observations".

Recent availability of comprehensive mouse cardiac hypertrophy microarray datasets, deposited in resources such as ArrayExpress [ 11] and Gene Expression Omnibus [ 12], makes it possible to investigate global molecular mechanisms of this phenotype.

Experimental designs that combine the CC, DO, and other resources, such as the comprehensive mouse knock-out panel, are being proposed to extend the scope of investigations using the CC strains.