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The homozygous mutant BTBR-PAHenu2 mouse has shown to be a remarkably good model for human PKU.
Recently, work in mouse has shown that the Hedgehog (Hh) pathway gene, Cdon, interacts with ethanol (Hong and Krauss, 2012).
However, a recent lineage study in the mouse has shown that Hoxa1 expression extends into r3 (Makki and Capecchi, 2011).
No DFF45/ICAD-deficient mouse has shown any developmental abnormality, but some cell types have shown reduced DNA fragmentation and DNA condensation and are partially resistant to undergo apoptosis (Zhang et al, 1998, 1999).
15, 16 Prior morphological assessment of the SMNΔ7 mouse has shown mild to severe denervation and moderate motor neuron loss that varies by spinal cord segment and muscles assessed.
Furthermore, a study on the mouse has shown that over-expression of ABCG5 and ABCG8 decreases diet-induced atherosclerosis, in association with reduced liver and plasma cholesterol levels [ 20].
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Studies in the mouse have shown that the Dlk1-Dio3 imprintedomainin on mouse chromosome 12 plays diverse roles in development.
In addition, previous studies in mouse have shown that this SRE element has a relevant effect on ELOVL6 expression [ 14].
However, studies with the asebia mouse have shown that sebaceous gland-derived glycerol contributes to stratum corneum hydration [ 22].
Studies in mouse have shown that RALDH3 was mainly involved in the frontonasal development and patterning of ocular structures [ 52].
Recent studies in the calcitonin gene knockout mouse have shown increases in bone mass and bone formation.
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