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Previous research in vitro has shown that Sal B stimulates increased ALP activity and osteocalcin secretion in a time- and dose-dependent manner [ 20].
The long-term physiological loading of rough and polished tapered stems in vitro has shown differences in performance, with greater interface pressures generated by the rough stems.
Expression and modification of murine and human anti-DNA antibodies in vitro has shown that removal of arginine residues often leads to a decrease in affinity for dsDNA [ 15, 19- 21].
Finally, analysis of apomyoglobin degradation in a purified system in vitro has shown that a disordered element in the middle of the polypeptide, in co-operation with helical segments located at the N-terminus, is required for proteolytic breakdown [ 19].
Recent work with the enantiomer of 25-HC in vitro has shown that effects of side-chain oxysterols on specific physiological pathways are nonenantioselective, providing compelling evidence that side-chain oxysterols exert their cholesterol-homeostatic effects in part through nonenantioselective modulation of membrane structure rather than wholly through enantioselective protein interactions.
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Studies in vitro have shown that proliferation of synovial cells of patients suffering from RA could be inhibited by somatostatin.
Mesenchymal stem cells in vitro have shown several interesting features such as multipotentiality, immunomodulation, and pro-regenerative capacities[9, 12, 15].
Gene expression studies of the bystander effect in vitro have shown that non-irradiated cells exposed medium from irradiated cells primarily induced over-expression of a large number of genes [26].
Studies in vitro have shown RVD is energy-dependent in astrocytes [35], [36].
A larger number of studies mainly performed in vitro have shown that MSC display immunomodulatory capacities.
Studies performed in vitro have shown that human iNKT can be directly cytotoxic against CD1d+ tumor cell targets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com