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Our measurements indicate that the real refraction for the mouse eye is probably myopic.

Knowledge of the optical aberrations of the mouse eye is important not only for understanding the visual capabilities of the mouse, but also because correcting these aberrations can improve the quality of in vivo images of the mouse retina.

On the other hand, the NA of the dilated mouse eye is approximately two times larger than the dilated human eye, presumably because the increase in light gathering power benefits the nocturnal mouse.

The amount of higher order aberrations measured over the 0.49 NA (2 mm pupil) mouse eye is similar to what is measured in the normal human eye over a 0.18 NA (6 mm pupil) [ 66] thus is correctible by AO.

Similar(56)

Before enucleation, the superior pole for each mouse eye was cauterized for orientation.

The modified filtering surgery in the mouse eye was performed as described in the text.

The adaptation for the optical qualities of the mouse eye was described previously [46].

Next, the Vav2 and Vav3 mRNA localization in mouse eye was examined by in situ hybridization (ISH) analysis (Figure 5B).

The mouse eye was first placed in fixative solution (4.0% paraformaldehyde, 0.5% glutaraldehyde in 0.1 M cacodylate buffer pH 7.2) for 5 min at room temperature (RT), after which the cornea was removed, and the lens was removed 10 min later.

The depletion of TUG1 in the developing mouse eye was found to block retinal development.

The role of higher order aberrations in reducing the retinal image quality of the mouse eye was assessed by computing the Strehl ratio.

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