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Consequently, also its hub genes were mostly enriched for mitochondrial genes.
Cluster iii involves 49 chemicals active in 12 to 90 assays, mostly enriched for GPCRs (both categories) and ion channels, as well as five others.
Taken together, in these consensus networks, the negatively correlated modules were mostly enriched for genes involved in neuronal and mitochondrial function, the positively correlated modules were mostly enriched for inflammatory pathway genes in the two cancers and for regulators of transcription and neurogenesis in DM1 and DM2 (Additional files 6, 7, 8 and 9 and Table 6).
A microarray assay showed that the CD11ahiFcγRIIIhi B cell-specific transcripts were mostly enriched for cytokines and cytokine receptors, suggesting that these new B cells may exert their specific function by secreting cytokines.
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These sedimentary facies and weathering crust zones are mostly enriched zones for natural gas (Cai et al. 2008; Jin 2010, 2012).
For each patient, one area of primary tumor and one area of metastasis were selected after scanning all cores for tumor epithelium mostly enriched with tumor infiltrating leukocytes (TILs), in accordance with a previously described protocol [ 21].
For the genes that have functional annotations, GO term enrichment revealed that the genes are mostly enriched in organic acid metabolic process (supplementary table S3, Supplementary Material online) and very interestingly also "leaf development" on this scaffold.
However 80% variants shared by both datasets (25% of all the detected variants) were homoplasmic and the only numerical, albeit not statistically significant discrepancy was recorded for very low-level heteroplasmic alleles (<10%), mostly enriched in LCLs.
Tumor necrosis factor (TNF) and MAPK signaling pathways were mostly enriched (Fig. S5).
Notably, these pathways are mostly enriched with up-regulated genes in cancer, suggesting a possible activation of these processes.
All eight overlapping HMR groups are mostly enriched in promoters and in contrary, tissue-specific HMRs are enriched mostly in introns and intergenic regions [ 14, 19].
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