Sentence examples for most reported gene from inspiring English sources

An additional limitation is that most reported gene expression profiles related to salt resistance have been derived from a single genotype [ 47– 47].

Unlike most reported gene delivery systems that are based on cationic derivatives or chemically modified RNAs, this nanoformula exploits an engineered RNA receptor, DPA/Zn.

While most reported gene fusions pertain to gain-of-function aberrations imparting neoplastic phenotypes, with high-throughput sequencing, fusions resulting in loss of function of tumor suppressors such as TP53 and PTEN have been identified as well [ 102].

Unlike most reported gene delivery systems, this NF system is not based on cationic derivatives to incorporate nucleic acid derivatives, and thus the NF demonstrated much lower nonspecific accumulation and toxicity yet higher tumor targetability and tumor-specific gene delivery efficacy after systemic administration than the conventional gene transfection agents.

One most reported gene from this region is Apolipoprotein E (APOE), which influences on lipid profiles and is associated with the development of both 2DM with and without CAD, and furthermore, it increased the risk among the subjects with obesity and/or smoking, conditions that are associated with high oxidative stress [ 36].

Glypican 3 (GPC3) was identified as the third most frequently reported gene, observed in 17 gene signatures.

Missense alterations were the most commonly reported gene alteration type from homozygous patients across all growth phenotypes, in agreement with the high frequency of missense alterations reported in patients with Morquio A (Fig. 2B, Tomatsu et al. 2005b, Hendriksz et al., 2013a].

24 Interestingly, the most frequently reported gene, HSPA1A, which showed decreased expression in MS in four studies, is also functionally connected to the MHC: it encodes for a heat shock protein, which is likely to be involved in MHC class I and II mediated antigen presentation.

Secondly, most of the reported gene transfer protocols for these organisms were based on electroporation [1], [2], [5], where higher electroporation efficiency was limited to only a few laboratories that used sophisticated customer-built cuvettes and pulse generator [2].

In order to further examine the potential role of these most frequently reported genes, they were analysed using pathway tools.

To conduct a systematic review of genome-wide expression studies in multiple sclerosis in order to identify the most frequently reported genes.