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Of the newer systems proposed, the Goseki classification is one of the most promising prognostic factors.
Altogether, the most promising prognostic CP marker for glioma patients thus far seems to be serum YKL-40 protein.
Among all these candidates, miR-21-5p is the most promising prognostic marker, yet further prospective validation studies are required before it can go into clinical usage.
So far, three tissue miRNAs (miR-21-5p, miR-29-3p, miR-148-3p) have been examined in multiple studies, of which miR-21-5p is the most promising prognostic marker, yet further prospective validation studies are required before it can go into clinical use.
Finally, this study was not designed to directly compare the performances of CD74 mRNA level vs mHLA-DR in predicting 28-day mortality after septic shock but to identify the most promising prognostic marker among several MHC class II related genes.
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As a whole, survivin appears to be the most promising diagnostic and prognostic markers in monitoring PCa.
In the present study a number of biological markers, larger than any previously investigated and selected among those considered as the most promising for their potential role as prognostic variable or indicator of response to chemotherapeutic regimens, were determined in parallel on each tumour.
Across independent studies, circulating miR-141 and miR-375 were the most promising miRNAs, suggested as diagnostic and prognostic markers for high risk PCa, and two miRNAs that were also decribed to be higher expressed in prostate cancer tissue compared to nonmalignant prostate tissue [ 66, 91, 95, 113].
Among the proposed biomarkers of sepsis, PCT appears to be the most promising in terms of its diagnostic and prognostic benefits.
The cellular "microcosm" is emerging as a most promising field in translational research, providing excellent diagnostic, prognostic and therapeutic tools for the management of human diseases.
We foresee the use of the most promising biological markers in the phases of prevention, diagnosis, prognostic assessment and drug design.
Related(16)
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