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Lymph node involvement is one of the most significant prognostic factors of patients with rectal cancer.
The MAPEC study plus other earlier conducted less refined trials document the asleep BP mean is the most significant prognostic marker of CVD morbidity and mortality.
Age, performance status, mental status, tumor grade and histology, and extent of surgical resection are among the most significant prognostic factors influencing survival.
The disease status of axillary lymph nodes (LNs) is the most significant prognostic factor for patients with breast cancer [4] [5].
Nuclear S100A7 expression emerged as the most significant prognostic marker for HNSCC (p = 0.006, Hazard's ratio (HR) = 7.6, 95% CI = 1.3 5.1).
In summary, our study indicates that firstly, BRCA1 is closely related to ERCC1, RRM1 and other genes like MZF1, but stands out as the most significant prognostic marker of relapse.
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The TNM stage proved to be the most significant independent prognostic factor for determining survival.
However, defects in the TP53 pathway consistently appear as the most significant adverse prognostic factor in CLL.
In a Cox multivariate analysis of survival VEGF expression was the most significant independent prognostic factor (P = 0.001).
A multivariant analysis incorporating desmin staining, treatment, histology, age and gender revealed that the two most significant independent prognostic factors were treatment and histology.
Lymph node involvement, depth of invasion, age, and tumor location have been identified as the most significant clinicopathologic prognostic factors[ 3, 4].
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Justyna Jupowicz-Kozak
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