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Exact(5)
The most frequent toxic therapy effects were haematological (grade 3 toxicity in seven patients, anaemia in three and neutropenia in four).
The most frequent toxic effect was treatment field erythema.
Myelosuppression was the most frequent toxic effect in both groups (Table 3).
The most frequent toxic agents were ethanol (18%), benzodiazepines (15%), paracetamol (11%), and opioids (11%).
As expected the most frequent toxic effect was myelosuppression with grade 3 4 neutropenia recorded in 51% of the courses and seven episodes of febrile neutropenia.
Similar(55)
The most frequent toxicity was myelosuppresion and the only toxic death was as a result of bleomycin-induced pulmonary fibrosis.
The most frequent toxicity was myelosuppression.
In phase I study in patients with advanced or metastatic solid tumors, brivanib demonstrated promising antiangiogenic and antitumor activity and manageable toxicity with most frequent serious toxic effects recorded being nausea, pyrexia, aspartate aminotransferase (AST) or alanine aminotransferase (ALT) elevations, and thrombocytopenia [ 80, 81].
The most frequent tic is eye blinking.
Grade 2 anorexia was the most frequent chemotherapy-related toxicity and no toxic death was noted.
Most frequent grade 3 4 observed toxic effects were neutropenia (60%) and hand foot syndrome (16%).
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