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Colorectal adenomas are the most frequent benign colorectal tumors.
Laryngeal papillomatosis is the most frequent benign neoplasia in children.
Pleomorphic adenoma was the most frequent benign neoplasm (89.94%) and adenoid cystic carcinoma represented the most prevalent malignant neoplasm (22.41%).
Lipoma and lipomatous variants are the most frequent benign STT, with prevalence ranging between 16% and 50% [1, 2, 3, 4].
These studies have either searched for specific markers by comparing a particular class of thyroid tumor to the corresponding normal tissue, or looked for markers of malignancy by examining the most frequent benign and malignant classes of thyroid tumor (usually the FTA and PTC classes).
The most frequent benign paediatric soft tissue tumours in the head and neck are hemangiomas.
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It is considered the most frequent intracranial benign tumor, of low lethality rate and unknown etiology.
Table 3 lists the most frequent locations of benign bone tumours, keeping in mind that exceptions to these rules may occur in everyday practice.
The most frequent causes of benign strictures of the biliary tree can be related to postoperative injury not only after open or video-laparoscopic cholecystectomy (VLC) but also after gastric or hepatic resection, portacaval shunt and bilio-enteric anastomosis [1].
Loss of heterozygosity at 9p21 was the most frequent alteration in benign hyperplastic lesions, followed by LOH at 3p21 and 17p13.
Also, HPV 6 and 11 were the most frequent genotype in benign lesions (respectively, 42.1% and 26.3%); but, surprisingly, HPV 16 was present in third position (15.8%), as a single infection, in this type of lesions.
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