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Our findings provide the most detailed structural understanding of periplasmic flagella and the surrounding cell envelope, which enable this enigmatic bacterium to efficiently penetrate tissue and to escape host immune responses.
The most detailed structural information available is for BR pre-mRNPs (Skoglund et al. 1983; Wetterberg et al. 2001).
Finally, X-ray crystallography and/or nuclear magnetic resonance (NMR) provide the most detailed structural information of the atomic interactions in a protein protein complex.
71– 74 Once a target protein protein interaction has been established, it is desirable to obtain the most detailed structural information at atomic resolution of the protein protein complex by X-ray crystallography and/or NMR experimental techniques.
The architectures of both photosystems have been determined by numerous techniques, but X-ray crystallography has provided the most detailed structural information for the four large membrane complexes catalyzing oxygenic photosynthesis (Nelson and Ben-Shem, 2004; Nelson and Yocum, 2006; Croce and van Amerongen, 2013; Nelson and Junge, 2015).
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Most of these studies are not based on detailed structural analysis, and thus some of them do not seem to be credible from the engineering point of view.
The most frequent highly destabilized cancer-associated mutant, R175H, has, however, eluded a detailed structural characterization, indicating the need for complementary techniques to study this and other unstable mutants.
For instance, the first studies of the structural basis of disease mutants in GPCRs, or the most detailed analysis of cellular GPCR signal transduction networks using a systems biology approach, have been carried out in rhodopsin.
The most detailed information relating to RACK1-biomolecule associations currently available, however, has emerged from structural studies with ribosomes.
The most important gene for the analysis of genetic relationships in members of the family Iridoviridae is the major capsid protein (MCP) gene because this gene product is a structural protein with highly conserved domains [ 6, 8, 9] that encapsulate the most detailed evolutionary information.
In particular, we provided detailed structural information that suggests that myolaminae are the principal intermediate-scale functional units throughout most of the LV.
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