Sentence examples for most conserved structural from inspiring English sources

In order to study human T-cell reactivity to the most conserved structural protein of Lassa virus, the glycoprotein 2 (GP2), seven GP2-specific CD4+ T-cell clones (TCCs) were generated from the lymphocytes of a Lassa antibody positive individual.

The "nucleophilic elbow" is the most conserved structural feature of the αβ hydrolase fold [ 38].

As the most conserved structural feature, T1 copper centers invariably contain two His residues and one Cys residue as equatorial copper ligands.

Furthermore, the Fingers-like domains start with a beta strand-alpha helix element and ends by a helix-beta-strand element, which are the two most conserved structural patterns in RAMPs (see above and Additional File 1).

From a structural point of view, the most conserved morphological feature of eukaryotic flagella is the axoneme, which is made of nine doublets of outer microtubules plus 2 central microtubules (so-called 9+2 axonemal structure).

According to the review of Carter and Thornburg [ 36], the most important conserved structural feature among the GLPs is a conserved amino acid sequence termed the germin box.

To date, the precise function of the middle part remains enigmatic, yet this part contains most of the conserved structural elements of class-A GPCRs, including a major hydrogen-bond network (MHN) formed by the hydrophilic "2.50-cavity" and hydrophobic "middle-cavity" (Fig. 1) (Zhang et al., 2013; Katritch et al., 2013; Angel et al., 2009).

The envelope protein (E) is the most conserved of flavivirus structural proteins and is the major protein found on the virion surface [ 19].

Also, in Figure 4 we show that simulations performed using the JTT model produce less accurate results, especially for the most conserved (low entropy) structural classes i and i+4.

In a departure from previously described protocols, we chose to focus HMM training exclusively on the most highly-conserved structural features that extend throughout the GPCR superfamily.

This second Bayesian network, which validated in vivo the predictions made in silico, had broadly similar topology (F score 0.861) and total network complexity and, most significantly, featured the same conserved structural hubs.