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Exact(5)
As of today, safety/toxicity evaluations are typically based on the appearance of gross morphological changes rather than the effects on a cellular level, the ability of excipients in modifying the pharmacological activity of an active drug could lead to toxicity evaluation in routine for each additive used in oral formulations.
These data suggest that currently the earliest detectable changes in monocytes differentiating into fibrocytes are morphological changes, rather than specific changes in receptor expression.
Our findings highlight the notion that morphological changes rather occur by modifying gene regulation than sequence (see [60]) and open interesting and new perspectives in the field of the study of lamprey regulatory sequences and comparative genomics.
However, the criteria for judging such transdifferentiation have been incomplete in many studies, often relying on genetic expression studies and morphological changes, rather than definitive proof of neuron-like characteristics such as synapse formation and appropriate electrophysiological properties.
Often the initial response of targeted therapy in mRCC is associated with tumour stabilization and morphological changes rather than a shrinkage in tumour size (Fig. 1), and the best response according to RECIST may be postponed until several months after initial drug administration.
Similar(55)
It is mostly associated with diet PCs 2 and 3 (sanguivory and nectarivory) (Table 1), but showing a shared morphological change, rather than a contrast.
Therefore, we consider morphological changes conditional rather than causing depression (Kronmüller et al. 2008), possibly by impairing mood transitions.
However these adaptations may be the result of morphological changes in the joint, rather than the cause.
Although loss of specific functions in neurodegenerative diseases is often attributed to loss of neurons, there is evidence that some manifestations of these diseases reflect alterations in neuronal function rather than morphological changes such as neuronal atrophy and loss.
Thus, the onset of both SIMA expression and morphological changes in TM were consistent with reactive rather than pre-existing field change phenomena.
The formation of turbulent small scales is initiated by the morphological changes in the flow through stretching and twisting rather than vice versa.
Related(14)
molecular changes rather
morphological changes prior
morphological changes very
morphological alterations rather
morphological changes however
morphological changes but
morphological features rather
morphological responses rather
morphological constraints rather
morphological characteristics rather
morphological differences rather
morphological mechanisms rather
morphological criteria rather
morphological traits rather
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Justyna Jupowicz-Kozak
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