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The chapter also deals with its ontogenetic development and the morphological changes it undergoes as a result of aging.
In this time series, the vacuole (V) is tracked for a longer period, revealing its movement and the striking morphological changes it undergoes.
Although S. cerevisiae induced by AHLs appeared morphological changes, it needed to further confirm whether such changes were driven by the regulatory effect of AHLs or 'carbon source' of AHLs.
While the data contained in the present study do not establish a causal link between the described molecular and morphological changes, it is likely that these phenomena are connected.
Although these cells were derived from livers with gross morphological changes, it is noteworthy that in all three-dimensional cultures examined they formed a unistratified epithelium with lumen formation.
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Furthermore, pretreatment of cells with PI3K or MAPK inhibitors demonstrated the specificity of these pathways in IGF-1 mediated latent TGF-β1 induced morphological changes as it prevented changes in morphology.
Nevertheless, OCT is actually the most useful tool for evaluating morphological changes because it best reflects recurrence of neovascular activity.
The prolong contact of esophageal mucosal membrane with acid and pepsin due to the impaired antireflux barrier can lead to morphological changes in it and to investigate the same, esophageal tissues were investigated for morphological changes using SEM [ 4].
The LSCC implants adhere to the host membrane and induce significant morphological changes of it, allowing visualizing microscopically the behavior of implanted tumor cells.
This heterogeneity is related not only to genetic, proteomic, or morphological changes but it is manifested in outlook, life quality, or survival of patients.
Although it may be that these factors have not played a major role in driving the morphological changes we measured, it is likely that we had insufficient sample sizes to detect all such linkages.
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