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The renal tubular epithelial cells displayed typical cobblestone morphology, but IL-1β induced profound morphological changes, characterized by shape elongation, dissociation from neighbouring cells and loss of their cobblestone monolayer pattern.
Knockdown of nestin in zebrafish embryo by morpholino injection causes distinct morphological changes characterized by small head, small eyes and overt hydrocephalus.
BOP exposure resulted in bilateral capillary damage, brain edema and neural morphological changes characterized by cell body shrinkage and nuclear pyknosis.
Typical apoptotic morphological changes characterized by loss of adherence, condensed cytoplasm, and formation of apoptotic bodies were observed when VECs were exposed to TNF α.
Along with these changes in surface phenotype, microglia undergo significant morphological changes, characterized by the retraction and thickening of their ramified processes and cell body hypertrophy [ 78].
Pre-treatment with 250 nM LAQ inhibited reactive morphological changes characterized by reorganization of the actin cytoskeleton including a spherical cell body and highly branched processes after IL-1β- and IFNγ-stimulation (supplementary Fig. 3).
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At 48 hours, cells started to undergo a distinct morphological change characterized by the occasional formation of long and rather thin cytoplasmic processes and of round cellular bodies (Figure 6A).
The cells also underwent a morphological change, characterized by enlargement and granulation.
Models based on daily intraperitoneal injections of 4.25% dextrose PD solution showed impaired peritoneal function accompanied by morphological peritoneal changes characterized by a fibroblast-like phenotype acquisition of mesothelial cells after 4 weeks [ 19, 26].
The surface morphological changes were characterized using SEM.
The chemical and morphological changes were characterized by using XPS and FE-SEM.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com