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ALDH1 was recently shown to be a more suitable marker to identify putative CSC of HNSCC and other epithelial cancers [11], [12], [13], [14], [15].
Therefore, it is important to find a more suitable marker for predicting the treatment outcome.
Further work is in progress in our laboratory to test the possibility of using fascin as a more suitable marker of neoangiogenesis than CD34 in lung cancers.
Rather, the enhanced idiA transcription and IdiA levels noted under iron limitation may be a more suitable marker for iron stress in Trichodesmium (Webb et al., 2001; Chappell & Webb, 2010).
In this respect, the skeletal muscle troponin-I subunit may be an earlier and more suitable marker for skeletal muscle damage than CPK [ 23] and it is widely used as a muscle damage maker after strenuous exercise [ 24].
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We have utilised two sampling approaches which provide more suitable markers to study the full process of 5-HT signalling using chromatography.
Although SNPs are generally considered as more suitable markers in the genome-wide association studies (GWASs), most reported SNP variants have relatively limited effects and explain only a small proportion of phenotypic variance [ 14].
For example, some works confirmed the association of high TNF-α levels with murine CM [ 59- 61], whereas others argued against such correlation, finding LT-α and IFN-γ as more suitable markers [ 44, 47, 62, 63].
The future MSCs research should focus on finding more suitable markers to isolate the source-specific MSCs, basic understanding of growth regulators in differentiation and trans-differentiation and site-specific homing that can revolutionize the cell regeneration therapy.
These results show that lymph node metastasis is composed of proliferating cells slower than that present in the primary tumour and it is hypothesized that the lymph node might not constitute an optimal environment for tumour cells proliferation or that Ki-67 might not be the more suitable proliferative marker for use in lymph node metastasis.
RFLP markers generated multiple loci more often than microsatellite markers, which suggests that microsatellite markers are more suitable than RFLP markers as consensus markers.
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Justyna Jupowicz-Kozak
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