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Absolute density may be a more appropriate marker in studies where body fat mass is investigated, such as in dietary studies [ 46- 48].
Phosphorylation of mTOR by Akt at serine 2448 might not correlate with mTOR activation, therefore, pmTOR may not necessary be involved with the development of HRPC, and a more appropriate marker of mTOR activation could be S6Kinase (Ruggero and Sonenberg, 2005).
Similar(58)
It is now increasingly recognized that adult stem cells, in contrast to their embryonic counterparts, have little if any regenerative capacity and that their presumed beneficial effects more likely involve paracrine signaling, in which case infarct size, perfusion, or left ventricular volumes might be more appropriate markers.
We do not believe, however, that this reservation detracts from the intrinsic value of our observations and of the process, and indeed further experiments may result in more appropriate markers of "activation" which influence cellular migration to be defined.
The factors which govern net cellular migration into and out of organs in vivo are likely highly complex and variable, and as yet relatively poorly understood, and in time it may be possible to identify more appropriate markers to "screen" for possible effects of cellular isolation on these processes.
Some investigators now believe that chromosome 17 polysomy is a more appropriate predictive marker [ 27, 28].
As argued earlier such measures are more appropriate as markers of sentinel events.
The Hoechst dye thus appears to be a more appropriate stem cell marker.
In some way it may be more appropriate for my milestone marker to be a sundial.
It would be more appropriate to list which markers are used to designate the haplogroups to ensure that they are comparable.
A more conservative choice of x=6.9 (a 1.5-LOD interval) is more appropriate to situations with dense markers, yielding approximate 95% coverage under dense marker scenarios.
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