Sentence examples for more stable domain from inspiring English sources

The two domains consequently engage in a thermodynamic tug-of-war in which the more stable domain forces the less stable domain to unfold.

The more stable domain (Tm about 74°C at pH 7.4) is further stabilized by KF and the domain with the lower Tm binds to and is stabilized by heparin (Table 1), as also corroborated by DSF.

In the latter case, genes encoding NRPSs whose products are involved in more conserved functions, such as the AARs, would be expected to have more stable domain architectures than those encoding proteins with niche-specific functions.

Recent studies suggest that functionally conserved genes, such as those involved in growth and development or other basic cellular processes, tend to experience both less variation in copy number [ 53] and more stable domain organizations [ 49] than genes involved in environmental and stress responses [ 53, 99].

Moreover, the reduction in processivity seems to depend on the stability of the domains flanking the internal initiation loop; a more stable domain both resists degradation itself and protects the domain on the other side of the loop from degradation, presumably because it extends the time that the substrates compete with each other for the motor sites.

For the heterodimer, the least stable domain is intermediate between the homodimer and WT when cross-linked and similar to the WT for the more stable domains.

This layer progressively transforms into a more stable apatite domain upon maturation in aqueous media.

Upon folding of the scFv fragment, a kinetic trap is populated whose escape rate is much faster with the more stable VH domain.

Importantly, iM10 did not only bind to the MITF coiled coil, but also to the markedly more stable HLHLZ domain of MITF.

However, perceptual organization, verbal and visual memory appear to be more stable cognitive domains in this population, given that their trajectory remained constant with age in all participants.

On the other hand, our DSF results suggested a possible aggregation tendency of the larger and more stable C-terminal domain and we investigated this feature in more detail.