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Owing to their more recent identification, and hindered by a lack of selective pharmacological tools, our understanding of the functions and signaling pathways of the non-Edg GPCRs is still in its infancy.
Enrichment of calls for protein-coding genes likely reflects the more recent identification of lncRNA genes.
In comparison with mTORC1, the biological function of mTORC2 is less well understood, in part because of its more recent identification (Sarbassov et al., 2005b).
However, the more recent identification of SCD5 orthologues in bovines [ 19], and chicken [ 20] suggested that the original SCD1/SCD5 duplication pre-dated the timing of the bird/reptile-mammal divergence.
Some of these have already been identified, such as the long-established role of mutations in TP53 and ATM, as well as the more recent identification of the poor prognostic significance of SF3B1 and BIRC3 mutations.
The types of immune cells present in myositis muscle were originally identified in the 1980s as predominantly CD4+ T cells and B cells in DM, and CD4+ and CD8+ T cells in IBM [ 1, 6- 8], with more recent identification of plasmacytoid dendritic cells in DM [ 9], myeloid dendritic cells in PM and IBM [ 3], and plasma cells in all three disorders [ 2].
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Some of our more recent identifications are of skeletons we've had for 15 years".
Building upon the preliminary findings of Discovery tags and more recent photo identification studies, satellite-monitored radio tags are now providing range and seasonal distribution information for many stocks of depleted large whales.
More recent data indicate that identification of variants of uncertain significance has continued to decline to approximately 5% of BRCA tests performed - a testament to the importance of maintaining and updating variant databases [ 22].
More recent studies using immunohistochemical identification of the two cell types have reported that the relative volume density of alpha cells vs beta cells tended to be higher [ 15, 16] or was significantly higher [ 3, 4, 6, 17– 19] in type 2 diabetic patients than in non-diabetic subjects.
Aspects relating to the metabolism of arsenosugars have become more complex because of the recent identification of dimethylarsenic sulfur and acetate compounds in urine of sheep that ingested seaweed (Hansen et al. 2003, 2004).
Related(20)
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Justyna Jupowicz-Kozak
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